Lüsen encompasses seven settlements. Most of the scattered settlements are situated on the orographic right side of the valley, such as Kreuz, Huben and Berg in the lower part of the valley, Flitt and parts of Petschied on the other hand are situated in the upper valley. The central villages Lüsen and Rungg have developed on a large fan. Three quarters of the area are covered by alpine pasture lands and forest. Lüsen's economy is based on livestock, small businesses and tourism.